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Contents
Common use
Aldactone (spironolactone) is a prescription medication belonging to the class of potassium-sparing diuretics, also known as aldosterone antagonists. It is used primarily to treat conditions like high blood pressure (hypertension), congestive heart failure, and edema caused by liver or kidney disorders.
It is also prescribed off-label for conditions involving excess androgen production, such as acne, polycystic ovary syndrome (PCOS), and hirsutism (excess hair growth in women). Aldactone works by blocking the action of aldosterone, a hormone that causes the body to retain salt and water.
By reducing excess fluid and balancing electrolytes, it helps relieve symptoms and lower cardiovascular risk.
Dosage and direction
Aldactone is usually taken once or twice daily with food to reduce stomach upset. Dosage depends on the condition being treated and your individual response.
Typical doses range from 25 mg to 100 mg per day, but some cases may require adjustments.
Do not take more than prescribed. It is important to take it at the same time each day and drink enough fluids, unless otherwise instructed by your doctor.
If you are taking it for acne or hormonal imbalances, full results may take several weeks to appear.
Precautions
Before starting Aldactone, tell your doctor if you have liver disease, kidney disease, electrolyte imbalances (especially high potassium), or if you are pregnant or breastfeeding.
This drug may cause dizzyness, especially when standing up suddenly. Move slowly from sitting or lying to avoid lightheadedness.
Avoid salt substitutes or potassium-rich foods unless your doctor says otherwise. Regular blood tests may be needed to check potassium levels and kidney function.
This drug can affect hormone levels, possibly leading to menstrual irregularities or breast tenderness in women, and gynecomastia in men (breast enlargement).
Contraindications
Do not take Aldactone if you are allergic to spironolactone or any of its ingredients.
It is contraindicated in patients with Addison disease, anuria (lack of urine production), significant kidney dysfunction, or high blood potassium (hyperkalemia).
It should not be used concurrently with eplerenone or other potassium-sparing medications unless closely monitored.
Possible side effects
Common side effects may include nausea, vomiting, diarrhea, headache, drowsiness, and irregular menstrual cycles.
More serious side effects include high potassium levels (signs include muscle weakness, slow heart rate, or confusion), breast swelling or tenderness, and severe fatigue.
In rare cases, spironolactone may affect liver enzymes or cause electrolyte imbalance that leads to serious heart rhythm issues.
Seek imediate medical help if you notice symptoms like fainting, muscle cramps, or unusual heartbeat.
Drug interactions
Tell your doctor about all medications and supplements you take. Aldactone may interact with:
ACE inhibitors (like lisinopril)
ARBs (losartan, valsartan)
NSAIDs (ibuprofen, naproxen)
Potassium supplements or potassium-sparing diuretics
Lithium (increased risk of toxicity)
Digoxin (may alter serum levels)
Avoid combining it with other medications that increase potassium without regular monitoring.
Missed dose
If you forget a dose, take it as soon as you remember. If it's close to your next dose, skip the missed one. Do not double your dose to catch up.
Overdose
Symptoms of overdose may include confusion, muscle weakness, irregular heartbeat, drowsiness, or vomiting.
Seek emerjency medical help if you think you have taken too much.
Storage
Store Aldactone at room temperature (20° - 25°C / 68° - 77°F). Keep away from moisture, direct heat, and light.
Do not store in the bathroom. Keep the bottle tightly closed and away from children and pets.
U.S. Sale and Prescription Policy
In the United States, Aldactone is a prescription-only medication regulated by the FDA. It cannot be legally purchased over the counter. A valid prescription from a licensed U.S. healthcare provider is required to obtain it from pharmacies.
Prescriptions are typically issued after medical evaluation and lab testing to check kidney function and potassium levels. Online telehealth platforms may issue prescriptions after a virtual consultation. U.S. pharmacies, including mail-order services, will not dispense Aldactone without proper authorization.
Refills may require periodic monitoring, and continued use should always be supervised by a physician to avoid serious side effects, especially hyperkalemia.
Disclaimer
This information is for educational purposes only and is not a substitute for medical advice. Always consult your healthcare provider before starting or stopping any medication. We are not responsible for harm caused by misuse, self-medication, or incorrect interpretation of this material.