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Contents
Common use
Coreg (carvedilol) is a beta-blocker that also blocks alpha-1 receptors, making it useful for treating high blood pressure (hypertension), heart failure, and improving survival following a heart attack. It works by relaxing blood vessels, slowing heart rate, and reducing the workload on the heart.
It is often part of long-term therapy for heart failure patients to improve heart function and reduce hospitalizations. Unlike traditional beta-blockers, Coreg also affects peripheral resistance, giving it additional benefit in managing chronic cardiovascular conditions.
Dosage and direction
Take Coreg exactly as prescribed. It is usually taken twice a day with food to reduce the risk of orthostatic hypotension (sudden blood pressure drops when standing).
Initial dosage for high blood pressure typically starts at 6.25 mg twice daily, and may be increased up to 25 mg twice daily based on response.
For heart failure, your doctor may start with a lower dose (e.g., 3.125 mg twice daily) and increase gradually.
Swallow the tablets whole; do not chew or crush. Always take doses at the same time daily.
Precautions
Inform your doctor if you have asthma, bronchitis, liver disease, diabetes, or thyroid disorders. Coreg may mask symptoms of low blood sugar or overactive thyroid.
Patients with asthma should use caution, as beta-blockers can cause breathing difficculties.
Do not suddenly stop taking Coreg - this may worsen heart symptoms or cause rebound hypertension.
Limit alchohol intake while on Coreg, as it may increase dizziness or drowsiness.
Contraindications
Do not use Coreg if you have severe liver impairment, asthma, second- or third-degree heart block, or severe bradycardia (slow heartbeat) unless a pacemaker is present.
It is also contraindicated in patients with cardiogenic shock or decompensated heart failure requiring IV drugs.
Possible side effects
Common side effects may include dizziness, fatigue, diarrhea, weight gain, or low blood pressure (especially when standing).
Serious side effects include extremely slow heart rate, fainting, breathing difficulties, or swelling in the legs.
Report any signs of allergic reactions like rash, itching, or swelling of the face or throat to your doctor imediately.
Drug interactions
Coreg may interact with:
Insulin or oral diabetes medications (masking symptoms of low blood sugar)
Other antihypertensives (e.g. clonidine, digoxin)
MAO inhibitors
CYP2D6 inhibitors (fluoxetine, paroxetine)
NSAIDs (may reduce antihypertensive effect)
Always provide your doctor a full list of medications and supplements before starting Coreg.
Missed dose
If you miss a dose, take it as soon as you remember unless it is close to the next dose. Never take two doses at once.
If more than a few days are missed, consult your doctor before restarting dosage may need to be re-titrated.
Overdose
Signs of overdose may include very slow heartbeat, difficulty breathing, severe drowsiness, seizures, or fainting. Seek emerjency help immediately if overdose is suspected.
Storage
Store Coreg at room temperature (20° - 25°C / 68° - 77°F). Protect from moisture, heat, and light. Keep the medication out of reach of children and pets.
U.S. Sale and Prescription Policy
In the United States, Coreg is a prescription-only medication, regulated by the FDA. A valid prescription from a licensed healthcare provider is required to obtain it legally from any U.S. pharmacy.
Prescriptions for Coreg are usually given after diagnosis of hypertension, heart failure, or post-heart attack care. It is often prescribed as part of a broader heart treatment plan, alongside ACE inhibitors or diuretics.
Generic carvedilol is available and covered by most insurance plans. Refills often require periodic monitoring of blood pressure, heart rate, and kidney function.
Online consultations may allow qualified patients to access prescriptions remotely, but dispensing always requires proper medical authorization.
Disclaimer
This text is provided for educational purposes only and does not replace the advice of a licensed healthcare professional. Always consult your doctor before starting, stopping, or changing medications. We are not responsble for any harm caused by misuse of this information.