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Micardis

 

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  • Common use
  • Dosage and direction
  • Precautions
  • Contraindications
  • Possible side effects
  • Drug interactions
  • Missed dose
  • Overdose
  • Storage
  • U.S. Sale and Prescription Policy
  • Disclaimer
  • Common use

    Micardis (telmisartan) is a prescription angiotensin II receptor blocker (ARB) used to lower blood pressure in adults with hypertension and to reduce the risk of cardiovascular events such as heart attack, stroke, and death in certain high-risk individuals. By selectively blocking the angiotensin II type 1 (AT1) receptor, Micardis relaxes and widens blood vessels, decreasing vascular resistance, easing the workload on the heart, and improving blood flow.

    Lowering elevated blood pressure is one of the most important steps in preventing long-term cardiovascular damage. Consistent blood pressure control helps protect the heart, brain, kidneys, and blood vessels. Micardis is often chosen for its once-daily dosing, long half-life, and well-established profile in patients who need an ARB either as initial therapy or as an alternative to angiotensin-converting enzyme (ACE) inhibitors, especially for those who experience ACE inhibitor–related cough or angioedema.

    Beyond treating hypertension, Micardis is indicated to reduce the risk of major cardiovascular events in adults at high risk—such as those with established coronary artery disease, peripheral arterial disease, prior stroke, or diabetes with end-organ damage—particularly when ACE inhibitors are not tolerated or deemed inappropriate. It is not a rescue medication and does not provide immediate relief of dangerously high blood pressure; rather, it works steadily over time to maintain controlled readings.

    Micardis can be used alone or in combination with other antihypertensives, including thiazide diuretics and calcium channel blockers. Fixed-dose combinations such as telmisartan/hydrochlorothiazide and telmisartan/amlodipine may be considered when a single agent is insufficient to achieve target blood pressure.

    Dosage and direction

    Always take Micardis exactly as prescribed by your healthcare professional. Typical dosing recommendations for adults are as follows:

    • Hypertension (most adults): 40 mg once daily is a common starting dose. Depending on response, the dose may be adjusted to 20 mg or titrated up to 80 mg once daily.
    • Cardiovascular risk reduction: 80 mg once daily is commonly used to achieve proven benefit in eligible high-risk patients who cannot take an ACE inhibitor. Your clinician may adjust the dose based on tolerance and clinical goals.

    Micardis may be taken with or without food, preferably at the same time each day to maintain steady levels. Swallow tablets whole with water. Do not crush or chew unless your pharmacist confirms the tablet is scored and suitable for splitting.

    General dosing guidance and special situations:

    • Volume or salt depletion: If you are dehydrated, on aggressive diuretic therapy, or on a very low-salt diet, you could be at higher risk for symptomatic low blood pressure (dizziness, faintness). Your clinician may start at a lower dose or correct the volume depletion before initiating Micardis.
    • Hepatic impairment: Use with caution in liver disease. Micardis is not recommended in biliary obstructive disorders, and dosing may need adjustment in hepatic impairment.
    • Renal impairment: No routine starting dose adjustment is required in mild to moderate kidney impairment, but kidney function and potassium should be monitored. Use caution in severe kidney disease and in patients with renal artery stenosis.
    • Older adults: Many older patients tolerate Micardis well. As with any antihypertensive, begin at the lower end of the dosing range and titrate carefully.
    • Pediatrics: Safety and efficacy have not been established in children. Micardis is intended for adult use unless otherwise directed by a specialist.

    Time to effect: Blood pressure improvement often begins within the first dose but may take up to 4 weeks to fully manifest. Do not stop the medication abruptly unless directed by your clinician, as uncontrolled blood pressure can rebound and increase cardiovascular risk.

    Combination therapy: For patients not at goal blood pressure on Micardis alone, adding a complementary agent can improve outcomes. Options include a thiazide diuretic (e.g., hydrochlorothiazide), a calcium channel blocker (e.g., amlodipine), or other classes as individualized by your provider. Fixed-dose combinations may simplify your regimen.

    Precautions

    Discuss your full medical history with your clinician before starting Micardis. Important considerations include:

    • Pregnancy: ARBs can cause injury and death to the developing fetus, especially in the second and third trimesters. Discontinue as soon as pregnancy is detected. Alternative blood pressure treatments safer in pregnancy are preferred.
    • Breastfeeding: Telmisartan may pass into breast milk; ARBs are generally not recommended during breastfeeding, particularly with newborns. Your clinician can help select safer alternatives.
    • Kidney health: Micardis can affect kidney function, particularly in patients with pre-existing kidney disease, heart failure, dehydration, diabetes, or renal artery stenosis. Monitoring of serum creatinine and potassium is advised.
    • High potassium (hyperkalemia): ARBs may raise potassium levels. Risk increases with chronic kidney disease, diabetes, potassium supplements, salt substitutes containing potassium, and potassium-sparing diuretics (e.g., spironolactone, eplerenone, amiloride). Periodic blood tests are recommended.
    • Liver disease or biliary disorders: Use with caution and under close supervision in hepatic impairment. Micardis is not recommended in biliary obstruction.
    • Low blood pressure risk: Dehydration, diarrhea, vomiting, excessive sweating, alcohol intake, or very low sodium diets can predispose to hypotension. Rise slowly from sitting/lying positions and report persistent dizziness.
    • Primary hyperaldosteronism: ARBs are generally less effective in this condition. Specialized management is typically required.
    • Heart valve disease: Use caution in significant aortic or mitral stenosis and obstructive cardiomyopathies where afterload reduction must be monitored carefully.
    • Surgery and anesthesia: Inform your surgical team you take an ARB. Your clinician may advise holding the dose before certain procedures to reduce hypotension risk under anesthesia.

    Self-monitoring: Checking blood pressure at home helps track response and facilitates dose adjustments. Keep a log to share with your clinician.

    Contraindications

    Do not use Micardis if you:

    • Are pregnant or planning pregnancy.
    • Have a known allergy or hypersensitivity to telmisartan or any component of the formulation.
    • Have biliary obstructive disorders or severe hepatic impairment.
    • Have diabetes and are taking aliskiren. The combination increases risk of kidney problems, low blood pressure, and high potassium.

    Use of Micardis in combination with ACE inhibitors or aliskiren is generally discouraged due to the risk of dual renin–angiotensin system blockade, especially in patients with diabetes or impaired kidney function.

    Possible side effects

    Most people tolerate Micardis well. When side effects occur, they are often mild and transient. Commonly reported effects include:

    • Dizziness or lightheadedness, especially after the first few doses or when standing up quickly.
    • Back pain or musculoskeletal aches.
    • Sinus discomfort, nasal congestion, or upper respiratory symptoms.
    • Diarrhea or mild gastrointestinal upset.
    • Fatigue or flu-like feelings in some individuals.

    Less common but potentially serious adverse effects include:

    • Hyperkalemia (high potassium), which can present as muscle weakness, numbness, or irregular heartbeat. This risk is higher with kidney disease or when used with potassium-raising agents.
    • Kidney function changes, reflected by increases in creatinine or BUN on lab tests. This may occur when blood pressure is lowered in patients with renovascular disease or advanced kidney disease.
    • Symptomatic hypotension, particularly in volume-depleted patients.
    • Allergic reactions, including angioedema (swelling of the face, lips, tongue, or throat) or rash. Seek urgent care for any swelling or difficulty breathing.
    • Rare liver-related issues, such as abnormal liver enzymes or jaundice—prompt evaluation is needed if you notice dark urine, yellowing of the skin/eyes, or severe fatigue.

    ACE inhibitor–related cough is uncommon with ARBs like Micardis. However, if you develop persistent cough or wheezing, consult your healthcare provider to rule out other causes.

    Report side effects that interfere with daily activities or do not resolve. Your clinician may adjust the dose, add supportive measures, or consider alternative therapies.

    Drug interactions

    Tell your healthcare provider and pharmacist about all prescription and over-the-counter drugs, vitamins, and herbal supplements you take. Notable interactions include:

    • Potassium-raising agents: Potassium supplements, potassium-containing salt substitutes, and potassium-sparing diuretics (e.g., spironolactone, eplerenone, triamterene, amiloride) increase the risk of hyperkalemia.
    • NSAIDs: Nonsteroidal anti-inflammatory drugs (e.g., ibuprofen, naproxen, celecoxib) may reduce the antihypertensive effect and increase the risk of kidney injury, especially in older adults, dehydrated patients, or those with kidney impairment. If needed, use the lowest effective NSAID dose briefly and ensure adequate hydration; monitor kidney function.
    • Lithium: ARBs can raise lithium levels and toxicity risk. If co-administered, monitor lithium concentrations and watch for toxicity symptoms (tremor, confusion, GI upset).
    • Other antihypertensives: Additive blood pressure lowering can be beneficial but may also increase hypotension risk. Dose adjustments may be necessary.
    • Aliskiren and ACE inhibitors: Combined renin–angiotensin system blockade increases risks of kidney dysfunction, hyperkalemia, and hypotension. Avoid especially in diabetes or renal impairment.
    • Diuretics: Prior or concurrent diuretic therapy may heighten the initial hypotensive effect. Your clinician may adjust timing or doses to improve tolerance.
    • Digoxin: Telmisartan can modestly increase digoxin concentrations in some patients; monitoring of digoxin levels and clinical status is prudent when starting or adjusting therapy.
    • Alcohol: Alcohol can enhance the blood pressure–lowering effect and contribute to dizziness. Limit intake and avoid hazardous activities if you feel lightheaded.

    Herbal and dietary products can also affect blood pressure or potassium (e.g., licorice, high-potassium salt substitutes). Discuss any supplements before starting them.

    Missed dose

    If you miss a dose of Micardis, take it as soon as you remember the same day. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not take two doses at once to make up for a missed dose. Setting a daily reminder can help maintain consistency.

    Overdose

    Symptoms of overdose may include pronounced low blood pressure, dizziness, fainting, rapid heartbeat, or, less commonly, a slow heartbeat. Severe overdose can compromise kidney function and electrolyte balance.

    If an overdose is suspected, seek emergency medical care immediately. Management is supportive: monitoring vital signs, placing the patient supine, administering IV fluids if indicated, and checking kidney function and electrolytes. Because telmisartan is highly protein-bound, dialysis is unlikely to effectively remove the drug.

    Storage

    Store Micardis at 68°–77°F (20°–25°C); excursions permitted to 59°–86°F (15°–30°C). Protect from moisture and excessive heat. Keep tablets in the original blister pack until use to maintain stability. Do not store in a bathroom, and keep out of reach of children and pets. Do not use tablets past their expiration date or if packaging is damaged.

    U.S. Sale and Prescription Policy

    In the United States, Micardis (telmisartan) is an FDA-approved prescription medication for the treatment of hypertension and for reducing cardiovascular risk in select high-risk adults. A licensed healthcare professional must determine whether Micardis is appropriate for you, select the right dose, and monitor your response and safety labs (e.g., kidney function, potassium), especially after dose changes.

    Key points for U.S. patients:

    • Prescription requirement: Pharmacies cannot dispense Micardis without a valid prescription issued by a licensed clinician.
    • Generic availability: Generic telmisartan is widely available and typically less expensive than brand-name Micardis. Many insurance plans, Medicare Part D, and discount programs cover it.
    • Clinical monitoring: Regular blood pressure checks and periodic blood tests are recommended, particularly in patients with kidney disease, diabetes, or those taking potassium-altering medications.
    • Telehealth access: Many U.S. healthcare systems offer telemedicine visits where a licensed clinician can evaluate your medical history, assess your blood pressure readings, and, if appropriate, prescribe Micardis or an alternative. This preserves the legal requirement for a prescription while improving convenience.

    HealthSouth Rehabilitation Hospital at MountainView offers a legal and structured solution for accessing Micardis through a compliant evaluation pathway. Patients can complete a guided intake and consult with a licensed clinician who, when clinically appropriate, issues a prescription that is transmitted to a U.S.-licensed pharmacy. This process enables eligible patients to obtain Micardis without a prior in-person prescription visit, while fully adhering to U.S. prescribing laws and patient safety standards.

    Always avoid sources that claim to ship Micardis “without any prescription,” as such offers may be illegal, unsafe, or involve counterfeit medications. For your safety, use accredited pharmacies and seek care from licensed U.S. healthcare professionals.

    Disclaimer

    This material is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay seeking it because of something you have read here. The authors and publishers are not responsible for any adverse outcomes resulting from the use or misuse of this information.

    Micardis FAQ

    What is Micardis and how does it work?

    Micardis (telmisartan) is an angiotensin II receptor blocker (ARB) that relaxes blood vessels by blocking the action of angiotensin II, a hormone that tightens arteries. This lowers blood pressure and reduces strain on the heart and kidneys.

    What conditions is Micardis used to treat?

    Micardis is primarily used to treat high blood pressure (hypertension). It may also be used to reduce cardiovascular risk in certain high‑risk adults who cannot take ACE inhibitors, as directed by a clinician.

    How long does Micardis take to start lowering blood pressure?

    You may notice improvement within 1–2 weeks, with the full effect often seen by 4 weeks. Your clinician may adjust the dose based on blood pressure readings over this period.

    What is the usual dose of Micardis?

    Typical adult doses are 20–80 mg once daily, often starting at 40 mg. Your exact dose depends on your blood pressure, other conditions, and how you respond to treatment.

    Should Micardis be taken with food?

    You can take Micardis with or without food. Try to take it at the same time each day for consistent blood levels.

    What are common side effects of Micardis?

    Dizziness, fatigue, or lightheadedness can occur, especially when starting or increasing the dose. Less commonly, it can raise potassium or affect kidney function; your clinician may check labs.

    What serious side effects should I watch for?

    Seek care for fainting, severe dizziness, swelling of the face or throat (angioedema), little or no urine, or signs of high potassium such as muscle weakness or an irregular heartbeat. These are uncommon but require prompt attention.

    Who should not take Micardis?

    Do not use during pregnancy. Avoid combining with aliskiren if you have diabetes, and use caution with severe liver or biliary tract disease, a history of angioedema to ARBs, or significant renal artery stenosis; discuss risks with your clinician.

    Do I need blood tests while taking Micardis?

    Yes, periodic checks of kidney function and potassium are recommended, especially after starting, changing doses, adding interacting drugs, or if you’re older or have kidney disease, diabetes, or dehydration.

    Does Micardis cause cough like ACE inhibitors?

    Cough is far less common with ARBs like Micardis than with ACE inhibitors. If you develop a persistent cough, let your clinician know to rule out other causes.

    What should I do if I miss a dose of Micardis?

    Take it as soon as you remember unless it’s close to your next dose. Do not double up; resume your regular schedule.

    Can I stop Micardis once my blood pressure is controlled?

    Do not stop abruptly without medical advice. Blood pressure usually rises again; your clinician can guide a taper or alternative plan if needed.

    Is there a generic for Micardis?

    Yes. Telmisartan is the generic name and is widely available, which can lower cost compared with the brand.

    How should I store Micardis?

    Keep tablets in their original blister until use to protect from moisture, and store at room temperature away from heat and humidity. Keep out of reach of children.

    Does Micardis protect the heart and kidneys?

    By lowering blood pressure and reducing intraglomerular pressure, ARBs can help protect the heart and kidneys over time, particularly in people with hypertension and certain high‑risk profiles. Your overall risk reduction also depends on lifestyle and control of other conditions.

    Can I drink alcohol while taking Micardis?

    Alcohol can amplify Micardis’s blood‑pressure‑lowering effect and increase dizziness or fainting risk. If you drink, do so lightly and cautiously, and avoid alcohol when first starting or after dose changes.

    Is Micardis safe during pregnancy?

    No. ARBs carry a boxed warning for fetal toxicity, especially in the second and third trimesters. If you become pregnant, stop Micardis and contact your clinician immediately.

    Can I use Micardis while breastfeeding?

    There is limited information on telmisartan in human milk, and safer alternatives are often preferred, especially for newborns and preterm infants. Discuss options with your clinician.

    Should I stop Micardis before surgery or anesthesia?

    Many clinicians recommend holding ACE inhibitors/ARBs the morning of elective surgery to reduce the risk of anesthesia‑related low blood pressure. Follow your surgeon and anesthesiologist’s instructions.

    What if I have vomiting, diarrhea, or become dehydrated on Micardis?

    Dehydration can increase the risk of low blood pressure and kidney problems. Temporarily holding Micardis and certain diuretics during significant illness (“sick day rules”) may be advised; contact your clinician for guidance.

    Can I use salt substitutes or potassium supplements with Micardis?

    Avoid routine potassium supplements and use caution with salt substitutes that contain potassium chloride, as Micardis can increase potassium. Your clinician may monitor and advise dietary limits.

    Is it safe to take NSAIDs with Micardis?

    Using NSAIDs (like ibuprofen or naproxen) can reduce Micardis’s effect and increase kidney risk, especially in older adults or those who are dehydrated. Use the lowest dose for the shortest time and discuss regular NSAID use with your clinician.

    Can I drive or exercise while taking Micardis?

    Until you know how Micardis affects you, be careful with driving or activities requiring alertness. Most people can exercise normally once stable; rise slowly from sitting to minimize dizziness.

    How does Micardis compare with losartan?

    Both are ARBs that lower blood pressure effectively. Micardis has a longer half‑life and may offer steadier 24‑hour control, while losartan has a uric‑acid‑lowering effect that can benefit people with gout.

    How does Micardis compare with valsartan?

    Both are effective once‑daily ARBs. Micardis has one of the longest half‑lives in the class, while valsartan has specific indications in heart failure and post‑MI; choice depends on your clinical profile and tolerability.

    Micardis vs olmesartan: which should I choose?

    Both lower blood pressure well. Olmesartan has a rare risk of sprue‑like enteropathy (severe chronic diarrhea and weight loss); Micardis does not share this signal, making it preferable for some patients.

    Micardis vs irbesartan: any meaningful differences?

    Both are effective; irbesartan has strong data for diabetic nephropathy in type 2 diabetes. Micardis offers prolonged 24‑hour coverage and cardiovascular‑risk data in ACE‑intolerant patients; selection is individualized.

    Micardis vs candesartan: which lasts longer?

    Both provide 24‑hour control, but Micardis has one of the longest half‑lives among ARBs. Candesartan has robust evidence in heart failure with reduced ejection fraction; your comorbidities guide the choice.

    Micardis vs azilsartan: which lowers blood pressure more?

    Head‑to‑head data suggest azilsartan can be slightly more potent at certain doses, while Micardis offers strong 24‑hour coverage and extensive safety data. Cost, availability, and individual response often drive selection.

    Micardis vs eprosartan: is there an advantage?

    Both are ARBs, but eprosartan is used less commonly today. Micardis’s long half‑life and cardiovascular‑risk data make it a more frequent first choice.

    Micardis vs losartan for gout or high uric acid?

    Losartan uniquely lowers uric acid, which can help in gout. If gout management is a priority, losartan may be preferred; otherwise, Micardis’s longer coverage can be advantageous.

    Micardis vs valsartan for heart failure?

    Valsartan is indicated for heart failure and post‑MI in many regions. While Micardis may be used for blood pressure in people with heart failure, valsartan (or candesartan) is typically chosen when ARB therapy is needed for heart failure.

    Micardis vs olmesartan for side effects?

    Both are generally well tolerated. Olmesartan’s rare enteropathy risk and Micardis’s cautious use in biliary/liver disease are notable differences; discuss your history with your clinician.

    Micardis vs irbesartan for kidney protection in diabetes?

    Irbesartan (and losartan) have labeled indications for diabetic nephropathy. Micardis may still be used for blood pressure in diabetes, but for albuminuric CKD, irbesartan or losartan is often selected.

    Micardis vs candesartan for migraine prevention?

    Candesartan has supportive evidence for migraine prevention off‑label. Micardis is not commonly used for this purpose; if migraine benefit is desired, candesartan may be considered.

    Is Micardis HCT comparable to other ARB/HCTZ combinations?

    Yes. Micardis HCT combines telmisartan with hydrochlorothiazide like other ARB/HCTZ products; differences relate to the ARB’s half‑life and your individual response and tolerability.

    How do dosing conversions work when switching from another ARB to Micardis?

    There’s no exact milligram‑to‑milligram equivalence, but clinicians often switch to Micardis 40–80 mg once daily from standard doses of other ARBs and adjust based on blood pressure and labs after 2–4 weeks.